Tuesday, November 19, 2019

BOTOX® Cosmetic (onabotulinumtoxinA) Important Information

BOTOX® Cosmetic (onabotulinumtoxinA) Important Information


BOTOX® Cosmetic is a prescription medicine that is injected into muscles and used to improve the look of moderate to severe frown lines between the eyebrows (glabellar lines) in people 18 to 65 years of age for a short period of time (temporary).


BOTOX® Cosmetic may cause serious side effects that can be life threatening. Call your doctor or get medical help right away if you have any of these problems any time (hours to weeks) after injection of BOTOX® Cosmetic:
Problems swallowing, speaking, or breathing, due to weakening of associated muscles, can be severe and result in loss of life. You are at the highest risk if these problems are pre-existing before injection. Swallowing problems may last for several months

Spread of toxin effects. The effect of botulinum toxin may affect areas away from the injection site and cause serious symptoms including: loss of strength and all-over muscle weakness, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice (dysphonia), trouble saying words clearly (dysarthria), loss of bladder control, trouble breathing, trouble swallowing. If this happens, do not drive a car, operate machinery, or do other dangerous activities

The dose of BOTOX® Cosmetic is not the same as, or comparable to, another botulinum toxin product.

There has not been a confirmed serious case of spread of toxin effect when BOTOX® Cosmetic has been used at the recommended dose to treat frown lines.

Serious and/or immediate allergic reactions have been reported. These reactions include: itching, rash, red itchy welts, wheezing, asthma symptoms, or dizziness or feeling faint. Tell your doctor or get medical help right away if you are wheezing or have asthma symptoms, or if you become dizzy or faint.

Do not take BOTOX® Cosmetic if you: are allergic to any of the ingredients in BOTOX® Cosmetic (see Medication Guide for ingredients); had an allergic reaction to any other botulinum toxin product such as Myobloc® (rimabotulinumtoxinB), Dysport® (abobotulinumtoxinA), or Xeomin® (incobotulinumtoxinA); have a skin infection at the planned injection site.
Tell your doctor about all your muscle or nerve conditions, such as amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease), myasthenia gravis, or Lambert-Eaton syndrome, as you may be at increased risk of serious side effects including severe dysphagia (difficulty swallowing) and respiratory compromise (difficulty breathing) from typical doses of BOTOX® Cosmetic.

Tell your doctor about all your medical conditions, including if you have: plans to have surgery; had surgery on your face; weakness of forehead muscles, such as trouble raising your eyebrows; drooping eyelids; any other abnormal facial change; are pregnant or plan to become pregnant (it is not known if BOTOX® Cosmetic can harm your unborn baby); are breast-feeding or plan to breast-feed (it is not known if BOTOX® Cosmetic passes into breast milk).
This product contains albumin taken from human blood. Steps taken during donor screening and product manufacturing processes make the risk of spreading viral diseases extremely rare. In theory, there is also an extremely rare risk of contracting Creutzfeldt-Jakob disease (CJD). No cases of spread of viral diseases or CJD have ever been reported for albumin.

Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal products. Using BOTOX® Cosmetic with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have received BOTOX® Cosmetic in the past.

Especially tell your doctor if you: have received any other botulinum toxin product in the last 4 months; have received injections of botulinum toxin, such as Myobloc®, Dysport®, or Xeomin® in the past (be sure your doctor knows exactly which product you received); have recently received an antibiotic by injection; take muscle relaxants; take an allergy or cold medicine; or take a sleep medicine.
Other side effects of BOTOX® Cosmetic include: dry mouth, discomfort or pain at the injection site, tiredness, headache, neck pain, and eye problems: double vision, blurred vision, decreased eyesight, drooping eyelids, swelling of your eyelids, and dry eyes.
For more information refer to the Medication Guide or talk with your doctor.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
Please see BOTOX® Cosmetic full Product Information including Boxed Warning and Medication Guide.

Monday, November 4, 2019

Lip Augmentation

Lip augmentation creates fuller, plumper lips and reduces fine wrinkles around the mouth. Lips may be injected with collagen or with fat transferred from another site in the patient's body. Both liquid collagen and fat are absorbed and repeat treatments are necessary to maintain results. Newer, longer-lasting options include implantable materials like AlloDerm and SoftForm.


A natural or synthetic biocompatible material, or the patient's own fat, is injected or implanted in the lips. One injection is usually sufficient to produce the desired result, which may be temporary, depending on the material used. Injections may need to be repeated periodically. Proper placement of the injected material is important. AlloDerm, a natural collagen sheet made from donated skin, is inserted through tiny incisions inside the corners of the mouth. Once the AlloDerm implant is in place, it eventually becomes integrated with the natural tissues. Gore-Tex, SoftForm and soft ePTFE are other synthetic implant options.

Further options include:

  • Autologen - injectable dermal implant material made from the patient's own skin.
  • Dermalogen - injectable Human Tissue Matrix (HTM) procured from donor tissue.
  • Fascia - injectable donor tissue made from the dense white connective tissue that supports body structure. Can also be done as a surgical implant.
  • HylaForm - a crystal-clear injectable gel; the hyaluronic acid in Hylaform is similar to that naturally found in the body.
  • Radiance - calcium hydroxylapatite
  • Restylane - crystal-clear injectable gel; the hyaluronic acid in Restylane is very close to that naturally found in the body.
Another augmentation choice is laser lip rejuvenation, which tightens the natural collagen and elastic tissue beneath the lips.

Monday, October 28, 2019

Danger zones for dermafillers !!!

The high risk areas for arterial/venous occlusion when injecting dermafillers are the temple, glabella, nose, cheek, nasolabial folds, lips, and lower face. It is virtually the entire face. Injury of vessels may result in embolisation (resulting in visual loss), blockages (tissue necrosis), severe bruising, and volume compression. There can also be injury to nerves.

Monday, October 21, 2019

Wrinkle Injections Medicine

Muscle relaxing injections serve best to smoothen out the face wrinkles.  They work by blocking the function of muscle that cause wrinkles.  Different types of injections are available and it is our choice to choose the best among them.

Wrinkles around mouth  is an issue of which lots of folks experience particularly ladies.   Majority of these facial lines could appear anywhere on your face although it seems that the most noticeable part is whenever it forms lines from the bottom of your nose all the way down to the edges of your mouth.
The presence of wrinkles around mouth affects your self-esteem.  They customarily appear on the area from the base of your nose down to your mouth.  The worse thing is that its location makes them so obvious.  That is why when you see them in the mirror you want them to be removed straight away.
It has long been suspected that wrinkles around mouth has been more of a problem for women than for men.  Those wrinkles are called perioral wrinkles, and a recent study indicates that biology may be the culprit in terms of women being more prone to them than men.
There are many factors that cause wrinkles around mouth.   The most typical is the excessive facial movements and expressions like when you're frowning, thinking too hard, smiling or annoyed.   Environmental components such as too much sun exposure and pollution can result into early aging that will be the reason behind your wrinkles.
People want to get rid of wrinkles around mouth as it can make a positive change to their entire appearance.  And one can adopt a lot of ways to get rid of wrinkles around mouth.  Since unhealthy skin can also be one the culprits, you can get rid of wrinkles around mouth, by making some substantial changes to your diet.  Usually a diet which constitutes of vitamin E filled fruits and vegetables can help you to combat wrinkles, and in certain cases, the development of wrinkles can get delayed as well.
One of the first sign of aging is the wrinkles around the mouth which are called the smile lines.  As the production of collagen slows down with aging, the skin's elasticity breaks down, resulting in those wrinkles.  It is further hastened by smoking and sun exposure without proper care.  But the good news is, there are many professional skin care products that will help you to reduce wrinkles around mouth.  There are some natural home remedies as well.
The most expensive skin care is not necessarily the best one either.  On the contrary, an inexpensive product may show tremendous results on your skin simply because it may contain more effective natural ingredients.  It is highly recommended that when choosing an anti-wrinkle product, select one with ingredients that are safe and natural, especially when using on wrinkles around mouth.

Thursday, October 17, 2019

Wrinkle Injections: Dysport Vs Botox

Dysport vs. Botox; what treatment is the best treatment for wrinkles and frown lines? Both drugs have the same active ingredient: Clostridium botulinim toxin type A. Both are approved by the US FDA. Both work in the same way, by paralyzing facial muscles. So what are the differences?

Wednesday, October 16, 2019

Dr. Patrick J. Treacy

We have all seen individuals whose mood has changed positively following BTX-A injection in the brow area. Now there is growing evidence that treatment of the glabellar area may actually be used to treat depression. In this paper Dr. Patrick Treacy looks at the current data to support this theory.
Depression affects over 120 million people globally, making it one of the leading causes of disability in the world. Although there are various effective treatments, therapeutic response remains unsatisfactory and depression can develop as a chronic condition in a considerable proportion of patients. Negative emotions, such as anger, fear, and sadness are prevalent in depression and also are associated with hyperactivity of the corrugator and procerus muscles in the glabellar region of the face. In 1872, Charles Darwin recognised these features as a very specific expression of sadness and attributed them to the activity of so-called ‘grief muscles’ in the glabellar region. He also formulated a new theory called the ‘facial feedback hypothesis’, which implied a mutual interaction between emotions and facial muscle activity. More recently, Larsen et al. have shown experimental evidence that voluntary contraction of facial muscles can channel emotions, which are conversely expressed by activation of these muscles.
Heckmann and others (1992) have published data suggesting that treatment of the glabellar region with botulinum toxin produces a change in facial expression from angry, sad, and fearful to happy and this can impact on emotional experience. Many therapists, including Sommer (2003) have shown that patients who have been treated in the glabellar area reported an increase in emotional wellbeing and reduced levels of fear and sadness beyond what would be expected from the cosmetic benefit alone. Hennenlotter (2009) went one stage further and showed that botulinum toxin treatment to the glabellar area stopped the activation of limbic brain regions normally seen during voluntary contraction of the corrugator and procerus muscles. This indicated that feedback from the facial musculature in this region in some way modulated the processing of emotions. Many other researchers have continued down this road with Havas (2010) noting that the processing time for sentences with negative affective connotation was prolonged in women after glabellar botulinum toxin treatment and Neal and Chartrand (2011) speculating that the treatment interfered with the ability to decode the facial expression of other people. This is where things were until recently with many authors suggesting that this capacity to counteract negative emotions could be put to some clinical use during the treatment of depression.

Wednesday, October 2, 2019


1.    Botox and fillers work the same way.
No, Botox (a brand of anti-wrinkle injection) and dermal fillers work differently and treat different concerns. Anti-wrinkle injections (Botox and Dysport) are muscle relaxants. Dermal fillers restore volume and hydration.
2.    Botox and fillers can remove movement and emotion from the face. 
Dosage is individualised to the client. The perfect amount of anti-wrinkle injections and dermal fillers should be tailored to allow natural expression.
3.    Botox is addictive. 
Cosmetic injections are not physiologically addictive; however, people may like the result so much that they work it into their grooming budget.
4.    Injectables are painful.
Everybody has a different pain threshold. Typically ice is sufficient to take the sting out of an anti-wrinkle treatment. 
When a client is having dermal fillers, we apply a pharmaceutical grade topical numbing cream prior to the treatment. The product itself also has an in built numbing agent, Lidocaine, to help alleviate any tenderness through the procedure. 
5.    It is easy to tell who has had injectables.
Ideally no one should suspect you have had cosmetic injections. The goal is to look like you are well rested and rejuvenated.
6.    Botox is expensive.
Depending on the level of your dosage and what product is used (Botox or Dysport), prices will vary.  
7.    All types of injectables are the same.
Laser Clinics Australia offers two different brands of anti-wrinkle injections, Dysport and Botox. There are slight differences in dosing and costing, but are both very similar in that they are both muscle relaxants, which create a smooth, rejuvenated and youthful appearance.
 8.    Fillers require downtime.
 There can be some downtime with cosmetic injections; however, they tend to be mild and transient.
 9.    If I stay out of the sun my botox will last longer.
No, the environment will have no impact on the effects of your treatment.
 10. Botox doesn’t last if you exercise regularly or aggressively .
There is no evidence-based research to suggest that this is the case. If you are noticing that longevity may be an issue, it is important to work with your injector to find an appropriate and safe dose that is both aesthetically pleasing and lasting.
 11. Botox can be poisonous. 
Botox and Dysport are TGA approved, and have a multitude of therapeutic uses.
For cosmetic purposes it is essential that an experienced and qualified doctor or registered nurse administers the treatment at manufacturers recommended dosage.
 12. The effects of botox are permanent.
Anti-wrinkle treatments typically last 3-4 months depending on the muscles injected and dose. As every client is different, the injector will create an individualised tailored plan to maintain a refreshed appearance. This may include incorporating dermal filler to achieve the desired aesthetic goal. 
 For more information visit www.laserclinics.com.au

Friday, September 20, 2019

What Are Facial Fillers?

What Are Facial Fillers?

Facial fillers are products such as collagen, hyaluronic acid and calcium hydroxyl apatite that rejuvenate facial skin by reducing or eliminating wrinkles, raising scar depressions, enhancing lips and replacing soft-tissue volume loss through facial injections. With age, our skin becomes more susceptible to wrinkles and sagging. Exposure to sun and years of muscle movement ( squinting, chewing, smiling ) contribute to tissue breakdown of the skin.

Facial fillers are temporary to long-lasting solutions administered through a few tiny facial injectionson specific areas of the face. Various types of facial fillers are available; each is designed with one or several purposes, such as wrinkle reduction and lip augmentation. A qualified dental or medical professional can help you determine which facial injections and what injectable fillers treatments are right for you. Facial fillers will volumize creases and folds in the face in areas that have lost fat and collagen as we age. Hyaluronic acid is the natural filler substance in your body. The face starts to lack volume and appears aged with deeper nasolabial folds, unaesthetic marionette lines, a deeper mentalis fold, the lips start to thin, and turning down the corners of the lips. Hyaluronic acid fillers such asRestylane and Juvederm are then injected extraorally right underneath these folds to replace the volume lost which creates a younger look in the face. Dermal fillers can be used for high lip line cases, asymmetrical lips around the mouth, lip augmentation, and completing cosmetic dentistry cases by creating a beautiful, young-looking frame around the teeth

Tuesday, August 20, 2019

It's like Botox, but with a different kind of sting.

In high street stores, the skin cream with a snake bite.........

An anti-ageing cream with an active ingredient designed to mimic the effect of the venom of a temple viper is available on the high street for the first time.

Known as Syn-ake, the chemical aims to banish wrinkles as effectively as the face-freezing injections.

Read more: http://www.dailymail.co.uk/femail/article-2072426/Syn-ake-The-Botox-bottle-anti-ageing-skin-cream-snake-bite.html#ixzz1gGQwwWUl

Read more: http://www.dailymail.co.uk/femail/article-2072426/Syn-ake-The-Botox-bottle-anti-ageing-skin-cream-snake-bite.html#ixzz1gGQlIz3K

Tuesday, August 13, 2019

Are you a good candidate for fillers?

The following are some common reason why you may want to consider fillers:
  • You have lines or wrinkles around your mouth, eyes or forehead.
  • You’d like to enhance the volume in areas such as the cheeks, jaw line or lips.
  • If you have scars and depressions in the skin resulting from acne, injury or congenital imperfections.

  1. Injectable fillers can help diminish the appearance of deep nasolabial lines.
  2. Adding volume to areas like the cheekbones can create a more defined contour.

Tuesday, August 6, 2019

How is Dermal Filler Different to Botox?

 by Dr Timothy Beazleigh

How is Dermal Filler Different to Botox?

People are often confused by the difference between Botox and dermal filler treatments, assuming they are the same. Whilst Botox is a muscle relaxant and is used to minimise muscle contraction thus reducing fine lines and wrinkles on facial movement, dermal filler is used specifically to restore volume to deeper, lines, creases and folds that are usually static i.e. permanently visible on the face even when the face isn’t moving.

Traditional areas to treat with standard dermal fillers – including Juvederm and Restylane – are the nasolabial folds (corner of the nostrils to corners of the mouth), marionette lines (corners of mouth to chin/jowls) and the smokers lines (above the top lip). Thicker, more volumising fillers including Juvederm Voluma are used specifically to the mid face region to augment cheek bones, restore volume and plumpness to the lower cheeks and redefine the chin and temples. Fillers are also used to enchance and recontour lips.

As a treatment with dermal fillers requires the needle to penetrate the dermis deeper than for a standard Botox treatment, there is usually more opportunity for bruising to occur as the blood vessels are not visible to the practitioner (beyond the superficial layer), but bruising is by no means a standard side effect and occurs in approximately 50% of treatments.

Juvederm is the filler of choice at Melior Clinics Botox & Facial Aesthetic London Clinic as, being monophasic, it is smooth in consistency and also contains a built in anaesthetic, making the process a lot more comfortable for the patient.

Friday, July 12, 2019

The science of rejuvenation....

The science of rejuvenation

What is aesthetic medicine?

No longer willing to accept the visible signs of aging, an increasing number of women and men are seeking treatments to help them look as vibrant as they feel.
Thanks to aesthetic medicine, millions of people around the world can now look and feel younger for longer. A fast-growing field, aesthetic medicine is the art of rejuvenating skin and enhancing facial beauty through safe, physician-administered treatments based on breakthrough science.

About fillers and botulinum toxin Type A.

Most popular aesthetic treatments are fillers and Botulinum toxins, which are well-tolerated, injectable treatments that help, smooth the appearance of wrinkles or compensate volume deficits creating a beautiful appearance.
Botulinum toxins are purified substances that relax the facial muscles stop them from contracting and smooth the skin. The degree of muscle contraction impairment can be varied to soften the lines while maintaining the ability to elevate your eyebrows.

Botulinum toxin Type A is very well tolerated and safe for longer-term use.

Fillers plump up wrinkles by replacing lost volume in the skin creating a more youthful appearance. There are many types of wrinkle fillers; some of them are based on hyaluronic acid or collagens which are known for their safety and lifting capacity.

Source:  Merz Aesthetics

Thursday, July 11, 2019

Wrinkle Injections - Methods

As far as the treatment process is concerned, wrinkle correction via injection is similar to wrinkle correction procedures with botulinum toxin, e.g. botox®. Only the active mechanism is different, which is why different substances are also injected. Whereas treatment using botulinum toxin, e.g. botox®, involves inhibiting the contraction of the muscles in order to smooth wrinkles, wrinkle injection using tissue filler achieves the smoothing of wrinkles by filling slackened parts of the skin, providing support for the tissue, or increasing the amount of moisture and elasticity in the skin through the injected material.

Possible tissue fillers used for this procedure are natural substances known as bio-implants, synthetic preparations, or one's own body fat. The described substances are injected under the wrinkles using fine needles under local anaesthesia; autologous fat (fat from one's own body) is removed from a separate spot on the body in advance via suction. Among the most commonly used bio-implants are collagen and hyaluronan; synthetic polylactic acid is also often inserted.

Collagen is a natural protein taken from animal skin that is cleansed and prepared for injection using a special process. Once it is injected under the wrinkles, it binds itself to the body's own collagen, fills up slackened skin parts, and forms a natural protective framework for the surrounding tissue. Swelling after the procedure generally goes down within 24 hours. Hyaluranon is what is called a natural polysaccharyl, which is responsible for the lubrication and elasticity of the skin. With increasing age, hyaluranon content in the skin decreases; this can be compensated through the injection of colorless gel in some cases, thus raising sunken skin tissue.

Crystalline polylactic acid likewise effects an increase in the volume of collagen fibres and stimulates the formation of new fibres, which ultimately leads to a soft buildup of tissue and resulting mitigation of wrinkles.
In order to obtain the most complete results, it may be necessary, depending on the characteristics of the wrinkles, to repeat the treatment involving the above-mentioned filling substances at intervals of 1-2 weeks. For injections of polylactic acid, there should be at least four weeks between treatments.

"Frown lines" (glabellar wrinkles) on the forehead as well as folds between the nose and mouth (nasolabial folds) can also typically be treated via the injection of autologous fat. The fat previously removed from another spot on the body under local anaesthesia is injected, thus achieving increased volume and tautening of the skin.