Muscle Relaxing Injections for Wrinkles

Proprietary Name	New Non-Proprietary Name
Botox / Botox Cosmetic	OnabotulinumtoxinA
Xeomin / Xeomin Cosmetic	IncobotulinumtoxinA
Dysport	AbobotulinumtoxinA
Myobloc	RimabotulinumtoxinB

For Canadians:

• All botulinum toxin products have usage information in the consumer section of the Product Monograph. Review it carefully with your health care practitioner.
• Discuss any concerns you may have about the risks and benefits of botulinum products with your health care practitioner.
• Pay close attention for any signs or symptoms of adverse events and seek immediate medical attention if you have unexpected difficulty swallowing or talking, trouble breathing, or muscle weakness following treatment with a botulinum toxin product.

Botox is indicated for the treatment of severe muscle spasm in the neck, eye and foot, for chronic migraines, incontinence, and for excessive sweating. Botox Cosmetic is indicated for cosmetic purposes, to treat facial wrinkling.

Dysport is indicated for the temporary improvement in the appearance of moderate to severe wrinkles in adult patients less than 65 years of age.

Xeomin is indicated for severe muscle spasm in the neck, eye and arm. Xeomin Cosmetic is indicated for the temporary improvement of moderate to severe frown lines in adult patients.

Myobloc is indicated for the treatment of adult patients with severe muscle spasm in the neck.

SOURCE: Health Canada

• Continue reporting any side-effects from the use of botulinum toxin products to MedEffect: Call toll-free at 1-866-234-2345, visit MedEffect Canada's web page on Adverse Reaction Reporting for information on how to report online, by mail or by fax.