WHY BOTOX MAY BE AGING YOUR FACE // Dr Rajani

How Often Can You Get Botox Injections?

 https://thestarbulletin.com/how-often-do-you-need-botox/

HX Wellness & Beauty

Suite #15  Araceli Coria, RN 416-888-0370  170K North Queen Street, Etobicoke 

with more than 20 years of experience offering cosmetic injectable services

Heavenly Xcapes Medical Spa

 https://stanfordartsreview.com/2023/09/24/mary-steenburgen-plastic-surgery/

Dermal Fillers Against Botox

 

dermal-fillers-against-botox-all-about-common-beauty-procedures-1012874/

Dr Patrick Treacy discusses hyaluronidase and his role in introducing it...

PREVENT FACIAL AGING CHANGES // Top 5 All Natural Anti Aging Skin

Cosmetic surgery crackdown to target Botox, fillers

 The rules around Botox, fillers, laser treatments and other non-surgical cosmetic treatments are set to be tightened in a crackdown by the nation’s medical regulator.

https://www.heraldsun.com.au/

Jeuveau vs. Botox: Similarities and Differences

 https://www.verywellhealth.com/jeuveau-vs-botox-similarities-and-differences-7566619

Cosmetic fillings are a standard, non-surgical procedure to reduce wrinkles, fine lines, and restore skin to appear more rejuvenated and youthful. 

Botox, one of the most widely used chemicals, has been the treatment choice for wrinkle reduction for years. Botox temporarily smooths frown lines and wrinkles between eyebrows, crow’s feet (near the outer corner of the eyes), and other areas in adults 18 and older.1

However, during the past few years, another Food and Drug Administration (FDA)-approved brand for cosmetic purposes has been overtaking the market, called Jeuveau, a relatively new cosmetic injectable that entered the market in 2019 as a competitor to Botox.

It is also nicknamed "Newtox," inferring that it is an upgraded version of the original Botox.2

While both products are effective, they share significant differences, such as their respective active ingredients and dosing regimens, and are subsequently not interchangeable.

Here’s an in-depth rundown of the shared differences, similarities, and proven efficacy of Jeuveau vs. Botox.

Uses and Ingredients

Jeuveau and Botox are injectables that smooth out wrinkles and fine lines on the face. When injected into specific facial muscles, the active ingredient blocks nerve signals to muscles, causing them to relax and smooth out wrinkles.

Both Jeuveau and Botox give temporary results, with effects lasting between three to six months. However, some people may experience longer-lasting results with Jeuveau.12

Jeuveau and Botox contain slightly different active ingredients, yet both belong to the same class of medicines called neurotoxins. More specifically, they contain a type of Botulinum neurotoxin (BNT).

Botulinum neurotoxin injections are used for both medical and cosmetic purposes. Depending on the requirements, the doses and muscles injected may differ.

BNT is a biological product developed using a bacteria called Clostridium botulinum (C. botulinum). It is injected into muscles, relaxing them and reducing excessive muscle contractions.3

Furthermore, Jeuveau and Botox are made from botulinum toxin type A, but the manufacturing processes and purification techniques to develop the final product are slightly different.4

Jeuveau

Jeuveau contains a neurotoxin, its active ingredient, called prabotulinumtoxinA. PrabotulinumtoxinA works by temporarily blocking nerve impulses to the muscles at the injection site, helping them relax and, in turn, helping smooth lines out.5

However, Jeuveau is not used in other conditions, including upper limb spasticity. Instead, Jeuveau is primarily used for treating frown lines between the eyebrows, also known as glabellar lines, in adults 18 and older.2

Notably, the proteins in Jeuveau are smaller and more uniform than Botox. Therefore, it may lead to a slightly quicker onset of action for Jeuveau (the time it takes for a drug to begin working).

Botox: Medical & Cosmetic

In comparison, Botox contains the neurotoxin called OnabotulinumtoxinA. Two versions of Botox are available in the market: cosmetic and medical.

Medical Botox treats conditions including neck muscle spasms, eye muscle spasms, migraine headaches, overactive bladder, urine leakage, and underarm sweating.

Medical Botox (OnabotulinumtoxinA) injection is also sometimes used to treat other conditions such as excessive sweating of the hands, wrinkles of the face, tremors (uncontrollable shaking of a body part), and anal fissures (a tear in the tissue near the rectal area).

It is also used to improve the ability to move in children with cerebral palsy (CP, a condition causing difficulty with movement and balance).

Botox Cosmetic is injected to temporarily smooth frown lines (wrinkles between the eyebrows), smooth crow's feet lines (wrinkles near the outer corner of the eye), and smooth forehead lines in adults aged 18 and older.

Botox blocks the nerve signals that cause uncontrollable tightening and movements of the muscle).6

Dosage Differences

Notable differences in the dosing regimen of Jeuveau and Botox are as follows.

However, your exact dose will be determined and most likely administered by a healthcare provider.

Botox

Your healthcare provider may administer the following when using Botox:1

Botox dose:

• Intramuscular injection: 50 and 100 units of vacuum-dried powder in a single-dose vial for reconstitution (adding a specific amount of water to a powder to make a liquid).

For glabellar lines:

• Inject 4 units (0.1 milliliters [mL]) into each of the five sites for a total dose of 20 units.

For muscles under the eyelids:

• 4 units/0.1 mL into three sites per side (six total injection points) for 24 units/0.6 mL (12 units per side).

For forehead lines:

• Inject 4 Units (0.1 mL) into each of five sites for a total dose of 20 units (together) with glabellar lines (lines in between eyebrows) is 40 units.

Jeuveau

Your healthcare provider may administer the following when using Jeuveau:2

Jeuveau dose:

• Intramuscular injection: 100-unit vacuum-dried powder in a single dose vial.
• For glabellar lines administration: 0.1 mL 4 units by intramuscular injection into each of five sites for a total dose of 20.

Which Is More Effective?

Jeuveau and Botox produce excellent results in reducing fine lines. One has been the drug of choice for decades, while the other is a new competitor with advanced benefits.

However, no head-to-head studies compare these two's effectiveness to determine which works better.

The clinical effects of Botox are seen on the first to the fourth days after injection and reach maximum level by one to four weeks and resolve after three to four months. Repeat the treatment to prolong the effects of Botox from six months to one year.7

The duration of the Botox effect varies among individuals due to differences in muscle arrangements. Different individuals may require different treatments of Botox.

In two trials, people with moderate to severe wrinkles and frown lines between the eyebrows improved 30 days after treatment with Jeuveau.

In a trial, 67% of people had temporary improvement of wrinkles between the eyebrows compared to 1% in the placebo group. In another trial, 71% of people had temporary improvement of wrinkles between the eyebrows compared to 1% of people who received a placebo.8

In a nutshell, Botox is such a trusted and widely used injectable, but Jeuveau is not less worth it at all. 

Side Effects & Safety

Cosmetic procedures are very effective and safe when done by a licensed healthcare provider. However, like every other drug, some side effects can be associated with Jeuveau and Botox.

Therefore, monitor yourself or a loved one closely for any potential side effects after taking Jeuveau or Botox.

Contact your healthcare provider immediately if any side effects emerge and continue to worsen. And in the case of a perceived medical emergency, call 911.

Common Side Effects

Some common side effects of Jeuveau and Botox include:12

• Eye dryness
  
• Symptoms of eye dryness
• Eye pain
• Eye irritation
• Photophobia (photosensitivity)
• Changes in vision
• injection site reactions

Severe Side Effects

Some of the more severe symptoms of Jeuveau and Botox include:12

• Muscle weakness
• Blurred vision
• Ptosis (drooping eyelids)
• Spread of toxin effects 
• Swallowing and breathing difficulties

Additionally, improper injection administration may cause neurotoxin to spread into adjacent muscles.9

Most adverse effects of cosmetic applications of botulinum toxin are mild and temporary.

The more severe side effects are secondary to poor injection technique, improper needle placement, and lack of experience.

Jeuveau vs. Botox: Which One to Take?

When selecting an option between Jeuveau and Botox, both can provide similar results in treating frown lines.

Personal preferences and comfort during the aesthetic treatment may also play a role in deciding. Some people prefer the slightly quicker onset of action associated with Jeuveau or a more extended history of success and familiarity with Botox.12

The treatment plan cost is another factor when comparing Jeuveau and Botox. Jeuveau may be less expensive than Botox in some cases.

Ultimately, the choice between Jeuveau and Botox will depend on the individual's specific needs and the person's medical history and aesthetic goals. Another aspect is the advice of the healthcare professional after analyzing your skin. 

Interactions

Avoid Jeuveau or Botox if you currently use any of the following:12

• Aminoglycosides (natural or semisynthetic antibiotics), such as Tobi Podhaler (tobramycin)
• Drugs that affect neuromuscular junction neuromuscular blocking agents (NMBAs), such as Quelicin (succinylcholine)
• Muscle relaxants, such as Lioresal (baclofen)
• Other botulinum products, such as Xeomin (incobotulinumtoxinA)
• Anticholinergic drugs, such as generic scopolamine

Before starting any drug treatments, contact your healthcare provider.

Summary

Jeuveau and Botox are injectable medications for treating facial wrinkles and other conditions. Both brands are similar in many ways, but there are significant differences in both these products.

Both have different active ingredients, time to onset of action, and duration of improvement results. They are not interchangeable.

Jeuveau is meant for use on the vertical lines between the eyebrows (glabellar lines). Botox is used for glabellar lines, forehead lines, and crow’s feet (lines around the eyes).12

Most people consider Jeuveau and Botox safe, but talking with a qualified healthcare provider is essential to choosing the best treatment plan. 

FREQUENTLY ASKED QUESTIONS

• Will I lose my sense of feeling where I have a Jeuveau or Botox injection?

  No. This treatment does not affect your ability to feel.12

• Are there any similar medications to Jeuveau or Botox?

  Other cosmetic brands, such as Dysport (abobotulinumtoxinA) and Xeomin (incobotulinumtoxinA), are available.6

  They may contain different active ingredients but are approved by the FDA for cosmetic treatments.10

‘Barbie Botox’ goes viral but doctors inject a note of caution over rise in procedure for neck slimmin

• Since the Barbie film was released, there has been demand for the cosmetic procedure that supposedly slims the neck to look like actress Margot Robbie’s
• The procedure, also known as ‘Trap Tox’, is usually used by doctors to inject into the trapezius muscles of the back to treat migraines and shoulder pain...
• https://www.scmp.com/news/world/united-states-canada/article/3233155/barbie-botox-goes-viral-doctors-inject-note-caution-over-rise-procedure-neck-slimming